On October 6, 1866, the Reno Gang of Seymour, Indiana, commited what is believed to have been the first train robbery in United States History.

"The Reno Gang's Reign of Terror"

Library of Congress page on the robbery (w/ video)

Page on Frank Reno, with a leter from the Vigilance committee who lynched him and his gang

IMDb page on "Rage at Dawn," a 1955 film based on the Reno Gang's exploits